May 22, 2015
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive muscular paralysis reflecting degeneration of motor neurons in the primary motor cortex, brain stem, and spinal cord.
Diagnosing ALS in the early stage of the disease can be difficult because of variable presentation, and common mimic disorders, according to Erik Pioro, MD, PhD, director of the section of amyotrophic lateral sclerosis and related disorders at Cleveland Clinic.