JAN 06

Radiation plus chemo reduces recurrence in some pancreatic cancer
Image provided by Mayo ClinicCANCER DIGEST – Jan. 5, 2016 – Pancreatic cancer patients who undergo chemotherapy and radiation after surgery were less likely to have the cancer recur within the five years following treatment than patients who only received chemotherapy after surgery.The study by the Mayo Clinic involved 458 patients who had pancreatic cancer surgery between 1987 and 2011. A total o

JAN 01

Ultrasound shown comparable to mammography for breast cancer detection
Portable ultrasound may be comparableto mammography for detecting breastcancerCANCER DIGEST – Dec. 31, 2015 – Ultrasound is as sensitive for detecting breast cancer as mammography, and should be considered for testing for the disease according to an international study.Researchers led by by Wendie Berg, MD, PhD, in the Department of Radiology at Magee-Women’s Hospital of the University of Pittsbur

DEC 24 2015

Gum disease increases breast cancer risk in postmenopausal women
History of smoking significantly affects the linkImage courtesy: National Instituteof Dental and Craniofacial ResearchCANCER DIGEST – Dec. 24, 2015 – Research has shown that taking care of your teeth and gums can prevent a lot of diseases you don’t want. Adding to the body of evidence, a new study shows that postmenopausal women with gum disease were more likely to develop breast cancer than women

DEC 14 2015

FDA approves new drug for sub-type of non-small cell lung cancer
CANCER DIGEST – Dec. 14, 2015 – The U.S. Food and Drug Administration approved Alecensa (alectinib) to treat people with specific form of non-small cell lung cancer.The Dec. 11 approval was for non-small cell lung tumors that have a mutation in the anaplastic lymphoma kinase (ALK) gene, which is present in several types of cancer in addition to about 5 percent of non-small cell lung cancers. The a

DEC 09 2015

5 of 6 at-risk women reject breast cancer prevention drug
CANCER DIGEST – Dec. 9, 2015 –Five in six women with increased risk of breast cancer turn down drugs likely to prevent the disease, according to research published in Annals of OncologyResearchers at Queen Mary University of London collected data from 21,000 women of all ages who were at increased risk of developing breast cancer and had taken part in 26 international studies. The women in these s

DEC 01 2015

Black breast cancer patients less likely to benefit from chemo before surgery
CANCER DIGEST – Dec. 1, 2015 – Among minority women treated with early chemotherapy, black women have worse outcomes than the other groups, a Yale Cancer Center analysis of the National Cancer Database shows.  Black, Hispanic, and Asian women typically develop advanced-stage breast cancer more often than white women. As a result, black women are more likely to receive chemotherapy prior to surgery

NOV 22 2015

New technology uses sound to kill pancreatic tumors
Ulster University's Professor John Callan led the team of researchers who made the pancreatic cancer breakthrough.CANCER DIGEST – Nov. 22, 2015 – A new approach using sound waves to destroy cancer cells is showing promise for treating pancreatic cancer.The treatment, called sonodynamic therapy (SDT) is the latest in a long line of approaches for delivering a toxic blow to cancer tumors without har
FDA approves new treatment for advanced pancreatic cancer
CANCER DIGEST – Nov. 21, 2015 – The FDA today approved Onivyde (irinotecan liposome injection), in combination with fluorouracil and leucovorin, to treat patients with advanced pancreatic cancer that has spread beyond the pancreas and who have been previously treated with gemcitabine-based chemotherapy.The effectiveness of Onivyde was demonstrated in a three-arm, randomized, open label study of 41

NOV 13 2015

Blood test could change cancer diagnosis
CANCER DIGEST – Nov. 13, 2015 – A new test of blood platelets can be used to detect, classify and pinpoint the location of cancer by analyzing as little as one drop of blood. Using this new method, researchers have been able to identify cancer with 96 percent accuracy, according to a study at Umeå University in Sweden recently published in the journal Cancer Cell.In the study, researchers from Ume

NOV 17

Anti-leukemia drug may also work against ovarian cancer
Ovarian cancer cells are shown forming small tumor. Image courtesy of University of GothenburgCANCER DIGEST – Nov. 17, 2014 – An experimental monoclonal antibody called cirmtuzumab is currently in a first-in-human phase 1 clinical trial to assess its safety and effectiveness in treating chronic lymphocytic leukemia CLL may also prove effective against ovarian cancer as well as others, a new study

NOV 12

Test predicts prostate cancer recurrence
YouTube courtesy Princess Margaret Cancer Centre University of TorontoCANCER DIGEST – Nov. 12, 2014 – Researchers have developed a genetic test to identify which men are at highest risk for prostate cancer recurrence after treatment with surgery or radiotherapy.The researchers developed the genetic test with two groups of patients. In the first group, the team analyzed DNA from initial diagnostic

NOV 10

New drug shows promise for people with BRCA1 or 2 cancers
CANCER DIGEST – Nov. 10, 2014 – People with certain cancers that stem from mutations of the BRCA1 or BRCA2 gene may soon have another treatment option to slow the cancer progression.In an early stage clinical trial of the twice-daily drug olaparib, 26 percent of patients had their tumors shrink or disappear for up to 7 months. The phase II trial was designed to determine whether tumors responded t

NOV 07

Colorectal cancer increasing in young adults
CANCER DIGEST – Nov. 7, 2011 – The number of people aged 20-34 with colorectal cancer increased by nearly 2 percent from 1975 to 2010, but declined overall by a little less than 1 percent.Using data from the Surveillance, Epidemiology and End Results (SEER) colorectal cancer registry, researchers from the University of Texas MD Anderson analyzed trends in four age ranges of 393,241 patients diagno

NOV 04

Combination therapy boosts melanoma survival by 50 percent
CANCER DIGEST – Nov. 4, 2014 – Patients with metastatic melanoma who were treated with an unusual combination of an immunotherapy with an immune stimulant survived 50 percent longer compared to patients who received only the immunotherapy.The study by Dana-Farber Cancer Institute scientists enrolled 245 patients with stage 3 or stage 4 metastatic melanoma who had been treated with other drugs. Amo

OCT 27

Canadian Medical Association gives thumbs down to PSA test
CANCER DIGEST – Oct. 27, 2014 – About 10 percent to 20 percent of men diagnosed with prostate cancer using PSA screening won’t have cancer. Overall 40 percent to 56 percent of men will be overdiagnosed, meaning they will be considered to have more or more aggressive cancer than they actually do, leading to invasive treatment. Surgery can cause postoperative complications, such as infection (in 11

OCT 23

Researchers find missing link between vitamin D and prostate cancer
CANCER DIGEST – Oct. 23, 2014 – A new study shows that a gene known to be stimulated into action by Vitamin D, is notably absent in samples of human prostate cancer driven by inflammation.Since demonstrating that Vitamin D stimulates production of GDF-15, researchers at the University of Colorado Cancer Center wondered if this gene might be a mechanism through which Vitamin D works in prostate can

OCT 20

Herceptin extends survival for in HER2 breast cancer
CANCER DIGEST – Oct. 20, 2014 – Women with early stage HER 2 positive breast cancer had a 37 percent improvement in survival and a 40 percent reduction in risk of cancer occurrence, when treated with Herceptin (trastuzumab) compared to patients treated with chemotherapy alone. Tumors with the human epidermal growth factor 2 protein, or just HER 2, tend to have more aggressive cancer.The findings t

Study Ranks CT Colonography Less Cost-Effective Than Stool Tests, …
Friday, August 15, 2011

Study Ranks CT Colonography Less Cost-Effective Than Stool Tests, Colonoscopy
CT colonography is better than not screening,
but is the most costly, least effective of the
screening methods available (Photo used
by permission of the RSNA)
Screening people for colorectal cancer using CT colonography is more cost-effective than not screening people at all, but not as effective as every other screening method currently available, a new cost-effectiveness study shows.

Led by Dr. David Vanness, assistant professor at the University of Wisconsin School of Medicine and Public Health, the researchers compared the cost-effectiveness of CT colonography for colorectal cancer screening in average-risk asymptomatic subjects in the United States aged 50 years. (
Link to published site)

Sunday, July 31, 2011

Eating a lot of fiber lowers breast cancer risk

Consuming high amounts of high-fiber
foods, such as legumes, may reduce
breast cancer risk. (Photo courtesy
U.S. Department of Agriculture) 
Women who participated in previous studies of diet and breast cancer and ate the most fiber had a 11 percent lower chance of developing breast cancer. That's the conclusion of a re-analysis of the data pooled from the studies, according to a Reuters report.

Chinese researchers led by Jia-Yi Dong of Soochow University in Suzhou, conducted the meta-analysis, which is a study that combines the data from previously conducted studies. In this case they combined data from 10 nutrition studies that individually had produced mixed results in terms finding a link between fiber consumption and breast cancer. (More)

Wednesday, July 27, 2011

Computer-aided mammograms no better for detecting cancer
CAD software marks screen-
ing mammogram for "second
read." (courtesy, Hologic, Inc.)

Adding computerized detection to screening mammography adds to the cost, but not the effectiveness in terms of catching potentially dangerous lesions, a new study finds.

In what may be the largest study yet to look at the real-world value of the widely used add-on for mammography, Dr. Joshua Fenton, an assistant professor in the UC Davis Department of Family and Community Medicine, and colleagues with the Breast Cancer Surveillance Consortium analyzed screening results of 1.6 million mammograms from 684,956 women in seven states. (More)

Saturday, July 23, 2011

BRUSSELS – July 23, 2011 (Cancer Digest) – A European panel recommended approval of Zytiga an oral drug that has been shown to extend survival in men with advanced prostate cancer. The European Committee for Medicinal Products is expected to approve the drug for sale in the next three months.

The drug approved by the U.S. FDA last April works by blocking the production of an enzyme required for the production of androgen hormones in the adrenal glands, the testes and by prostate tumors themselves. (More)

An Oxford study of nearly 1.3
million women found a 16
percent increase in cancer risk for
every four inches above five feet.
Thursday, July 21, 2011

OXFORD, UK – July 23, 2011 (Cancer Digest) – Led by Dr. Jane Green, the Oxford University study followed nearly 1.3 million middle-aged women for five years between 1996 and 2001. They gathered information about about height and other factors relevant to cancer. They published their findings today in The Lancet Oncology.

"Many previous studies have looked at height and cancer risk- most of  them were not large enough to compare risk across different types of cancer," the 5'7" Green told Cancer Digest in an e-mail interview,  "or to look in detail at other factors such as smoking. We were able to do this in our study of 1.3 million women." (More)

Sunday, July 17, 2011

ZURICH – July 15, 2011 (Cancer Digest) – Swiss pharmaceutical giant, Hoffman-La Roche announced that it will seek FDA and European approval for its breast cancer drug pertuzumab, according to the Wall Street Journal, Reuters and others.

The drug works by slowing the growth of the cancer-causing protein HER2, and has been shown in early trials to prolong progression-free survival, or lengthen the time that the cancer does not get worse, when used in combination with Roche’s Herceptin®. (More)

Malignant mesothelioma, indicated
by yellow arrows, is one of the cancers
in which men are more likely to die
than women. (courtesy Wikipedia, by
Tuesday, July 12, 2011

BETHESDA – July 12, 2011 (Cancer Digest) – It may not surprise many that men diagnosed with cancer are more likely to die of the disease than women. A new study, however, quantifies the differences in mortality between men and women for a variety of cancers.

The study’s lead author Michael Cook, a researcher in the division of epidemiology and genetics at the National Cancer Institute and colleagues published their findings today in the journal Cancer, Epidemiology, Biomarkers & Prevention.

The study reported widely by Reuters, Medical News Today and the Seattle Times analyzed 36 types of cancer by gender over the 30-year period between 1977 and 2006. (More)

The trachea or windpipe is the
primary airway serving
the lungs. (Diagram
from Wikipedia)
Monday, July 11, 2011

STOCKHOLM – July 11, 2011 (Cancer Digest) – The day when you go in for a periodic checkup and have a few body parts replaced with new ones grown from your own cells is much closer than you might think.

A 36-year-old African man with advanced cancer of the windpipe (trachea) received an artificial trachea implant that was grown in the laboratory using the patient’s own stem cells. NPR and others reported the first-of-its-kind transplant Monday, a month after the transplant took place. The researchers say the man  had recovered fully and would return home later this week. (More)


A safe and effective leukemia pill proves concept
SEATTLE -- Apr. 5, 2001 (cancerfacts.com) -- A pill that
halts a common type of leukemia has dramatically proven the concept that targeting the genetic basis of disease can work. See full story

Agent shown to suppress marrow transplant reactions in mice
SEATTLE -- May 3 2000 cancerfacts.com-- Researchers have developed a new drug that promises to prevent one of the most serious side effects of marrow transplantation. See full story

Alcohol boosts breast cancer risk for high-risk families
SEATTLE – July 30, 2001 (cancerfacts.com) --Drinking alcohol may boost the risk of breast cancer but only for women with a family history of cancer, say researchers in a public health study. See full story

Another new drug for rare leukemia surprises researchers
SEATTLE – July 26, 2001 (cancerfacts.com) -- Another leukemia may be on the verge of yielding to a newly developed drug if early tests are borne out in larger studies. See full story

Are seed implants for prostate cancer effective?
SEATTLE, Apr. 3, 2001 (cancerfacts.com) -- Without clinical trials comparing "seed implants" with standard treatments, the effectiveness of the popular radiation therapy for prostate cancer cannot be determined. See full story

Better marker for oral cancer
SEATTLE -- Apr. 27, 2001 (cancerfacts.com) -- The DNA in cells forming white patches in the mouth may predict oral cancer say Norwegian researchers. See full story

Bone marrow stem cells can transform into lung, liver
BALTIMORE -- May 4, 2001 (cancerfacts.com) -- Researchers have shown for the first time that transplanted bone marrow stem cells can not only reconstitute bone marrow, but also specialized cells lining the intestines, lung and skin. See full story

Breast implants cleared as cancer risk
SEATTLE -- Apr. 28, 2001 (cancerfacts.com) -- Silicon breast implants do not increase the risk of most types of cancer, but were associated with higher risks for lung and brain cancers according to one of the largest studies of these women to date. See full story

Breast pump detects women at higher risk for breast cancer
SAN FRANCISCO -- Dec. 4, 2001 -- A simple, non-invasive technique that can be performed in doctors’ offices has been shown to help predict women who are at increased risk of breast cancer. See full story

Breast self-exams do not increase survival
SEATTLE -- Oct. 1, 2002 -- Women taught breast self-examination more often detected breast tumors than women who did not perform the exams, but they did not detect the tumors early enough to make a difference in survival. See full story

Canadian panel recommends against breast self-exams
TORONTO -- June 26, 2001 (cancerfacts.com) -- Performing monthly breast self-examinations may be doing women more harm than good say researchers who examined the results of seven studies of the practice involving nearly 1 million women. See full story

Certain types of virus closely linked to cervical cancer
SEATTLE – July 25, 2002 -- Women infected with certain strains of a sexually transmitted virus are 100 times more likely to develop cervical cancer than women not infected with the virus say Dutch scientists. See full story

Cervical cancer virus more common than thought
SEATTLE – Nov. 13, 2002 (cancerfacts.com) -- Nearly 25 percent of women in the United States between age 20 and 29 are infected with a virus linked to half of all cervical cancers according to a new study. See full story

Chemo after surgery increases lung cancer survival
SEATTLE – Jan. 22, 2004 (cancerfacts.com) – Adding chemotherapy to surgery increases both cancer-free and overall survival among patients with non-small-cell lung cancer according to a new study. See full story

Cholesterol drugs don't increase breast cancer risk
SEATTLE – April 28, 2004 (cancerfacts.com) – Women who use cholesterol-lowering drugs, called statins, do not have an increased risk of breast cancer, in fact they may be reducing their risk, according to a new study. See full story

Combo therapy best for stomach cancer
SEATTLE – Sep 6, 2001 A combination of therapies significantly boosts survival time as compared to surgery alone for patients with stomach cancer say researchers. See full story

Common virus may make Hodgkin's Disease more aggressive
SEATTLE -- Apr. 19, 2001 (cancerfacts.com) -- A common virus may make a form of blood cancer more aggressive in older women, say researchers in a new study. See full story

Company warns of counterfeit drug
SEATTLE -- May 18, 2001 (cancerfacts.com) -- In a potentially life-threatening case of counterfeiting, someone is distributing a fake version of a drug commonly used by cancer patients undergoing chemotherapy. See full story

Double mastectomy prevents breast cancer in high-risk women
SEATTLE -- July 19, 2001 (cancerfacts.com) -- Women who carry one of two mutated genes that puts them at high risk for breast cancer, may cut their risk by having both breasts removed, according to a new Dutch study. See full story

Drinking hot tea may protect against skin cancer
SEATTLE – Aug. 22, 2001 (cancerfacts.com) -- Drinking hot black tea may protect against skin cancer, according to results of the first large-scale clinical study to investigate the potential of tea and citrus peel to prevent skin cancer in humans. See full story

Drug may help with prostate cancer that has spread to bone
SEATTLE – Oct. 4, 2002 (cancerfacts.com) -- A drug shown to benefit women with advanced breast cancer may also help men with advanced prostate cancer that has spread to bone, but not without side effects, according to a new study. See full story

Drug slows prostate cancer progression
SEATTLE – Aug. 10, 2001 (cancerfacts.com) -- A drug that slows the progression of prostate cancer may allow men to lead more normal lives longer even if the drug cannot cure the cancer. See full story

Early results show new regimen promising for prostate cancer
CHICAGO – May 2, 2001 (cancerfacts.com) -- A new combination chemotherapy and steroid therapy appears promising for men with advanced prostate cancer that no longer responds to hormone therapy, say researchers following a small multi-center study. See full story

Free radical damage linked to cancer risk after age 60
SEATTLE -- Aug. 16, 2001 (cancerfacts.com) -- For the first time, scientists have identified a mechanism for age-related accumulation of DNA damage in prostate cells that explains why a man's risk of prostate cancer dramatically increases around age 60. See full story

Hair color and artificial tanning boost skin cancer risk
OSLO, Norway – Oct. 15, 2003 (cancerfacts.com) – Young women who regualarly use tanning beds may be boosting their risk of a deadly form of skin cancer by as much as 55 percent, say researchers. See full story

Hormones may block recurrent breast cancer
SEATTLE -- May 16, 2001 (cancerfacts.com) -- Women who took hormones after being diagnosed for breast cancer cut their risk of recurrent breast cancer in half and their risk of dying from breast cancer by one-third according to a new study. See full story

Keyhole surgery equal to conventional surgery
HONG KONG – April 10, 2004 (cancerfacts.com) – Using a small-incision surgical technique, called laparoscopy, to treat colorectal cancer offers similar chance of surviving 5 years as conventional open-abdomen surgery, according to a new study. See full story

Link grows between breast cancer and hormone therapy
SEATTLE – Feb. 13, 2002 (cancerfacts.com) --A new study adds to a growing body of evidence that long-term hormone replacement therapy increases women’s chances of breast cancer. See full story

Long-term exercise cuts breast cancer risk
ATLANTA – July 17, 2001 (cancerfacts.com) -- Women over 50 years old who engage in highly active recreation over a long period may reduce their breast cancer risk by two-thirds as compared to women who seldom exercise, say researchers in a new study. See full story

Longer survival with radiation and hormone therapy
GRENOBLE -- July 12, 2002 (cancerfacts.com) -- Men with advanced prostate cancer may live twice as long when treated with hormone therapy in conjunction with radiation compared to men treated with radiation alone. See full story

Mackerel, salmon, herring may prevent prostate cancer
SEATTLE -- June 1, 2001 (cancerfacts.com) -- Men who eat even moderate amounts of fish that have a high oil content may significantly reduce their risk of prostate cancer according to Swedish researchers. See full story

Needle in the haystack method detects colon cancer
BALTIMORE – June 7, 2001 (cancerfacts.com) -- Researchers have successfully extracted DNA from stool samples and reliably detected mutations linked to colon cancer. See full story

New drug as effective, safer for ovarian cancer
RARITAN, NJ -- July 25, 2001 -- A new version of an effective drug for ovarian cancer may be as effective as current drugs but hold fewer harmful side effects according to results of one of the largest clinical trials ever conducted for ovarian cancer. See full story

New drug compares well to standard for pancreatic cancer
SEATTLE -- Aug. 1, 2001 (cancerfacts.com) -- A drug designed to choke off the blood supply of tumors in the pancreas offers a similar survival benefit compared to the standard chemotherapy agent, but caused fewer harmful side effects, researchers report. See full story

New target identified to stop cancer spread
SEATTLE – Sep. 19, 2001 -- Researchers have identified a gene in normal cells that appears to block the invasion and spread of cancer cells, a process known as metastasis. See full story

No link found between breast cancer and electrical fields
SEATTLE – Mar. 8, 2002 (cancerfacts.com) -- A new study has found no link between breast cancer and exposure to the electrical radiation given off by household wiring and appliances. See full story

Pill for colon cancer appears to be equal to IV chemo
SEATTLE – Apr. 17, 2001 (cancerfacts.com) -- Taking a pill for advanced colorectal cancer is as effective as a standard intravenous chemotherapy regimen, but doesn't make patients feel as sick, say researchers in a new study. See full story

Poliovirus modified to combat brain cancer
ORLANDO, FLA. -- May 22, 2001 (cancerfacts.com) -- Scientists using a cross between two viruses have successfully killed brain tumors in mice. See full story

Protein variations may explain breast cancer deaths in Blacks
SEATTLE. – Feb. 8, 2002 (cancerfacts.com) -- Differences in the way breast tumors process estrogen may partly explain why breast cancer in African-American women is fatal more often. See full story

Researchers warn about chemo combination
SEATTLE – May 17, 2001 (cancerfacts.com) -- Researchers treating patients with advanced colorectal cancer warned today that a FDA-approved chemotherapy regimen using three agents may have a higher fatality rate than previously has been shown. See full story

Risk of cancer higher among people with common stomach acid condition
More people who suffer from Barrett’s esophagus, a chronic condition of the lower throat caused by stomach acid reflux, may be at higher risk of cancer than previously thought, say Seattle researchers. See full story

Study raises questions about diet and prostate cancer
SEATTLE -- Aug. 29, 2002 (cancerfacts.com) -- A low-fat, high-fiber diet rich in fruits and vegetables may not affect men's risk of prostate cancer after all, according to one of the first studies to actually test the theory with an experiment. See full story

Study shows how vitamin E might prevent or treat prostate cancer
SEATTLE – May 31, 2002 (cancerfacts.com) -- Scientists have discovered for the first time how vitamin E interferes with internal cell mechanisms to prevent or slow the growth of prostate cancer. See full story

Surgery for ulcers linked to pancreatic cancer
SEATTLE -- May 2, 2002 -- People who have surgery for peptic ulcers are more likely to develop pancreatic cancer years later, according to findings of a Dutch and American research group. See full story

Survival extended with new treatment for non-Hodgkin's
BASEL, SWITZERLAND, 24 Jan. 2002 (cancerfacts.com) -- The standard chemotherapy combined with the drug rituximab produced the most significant survival gains in two decades for patients with for a common type of lymphoma, a European study shows. See full story

Tamoxifen may help some with breast cancer gene
SEATTLE -- Nov. 14, 2001 (cancerfacts.com) -- A new study shows that the breast cancer prevention drug tamoxifen appears to offer good news for women who carry one of two breast cancer genes See full story

Too much moo may up prostate cancer risk
SEATTLE -- Sep. 24, 2001 (cancerfacts.com) Got milk? Too much may boost the risk of prostate cancer according to a new study. See full story

Treatment for head and neck cancer may extend survival
PITTSBURGH -- June 28, 2001 (cancerfacts.com) -- Treating head and neck cancer patients with a combination of the biologic agents normally found in the body may lead to improved survival according to a new study. See full story

Vaccine for melanoma doubles 5-year survival
SANTA MONICA, Calif. -- Nov. 27, 2002 -- A combination of surgery and vaccine therapy appears to nearly double the survival of patients with advanced melanoma, compared to similar patients treated with surgery alone. See full story

Vaccine may prevent some forms of cervical cancer
SEATTLE -- Nov. 21, 2002 (cancerfacts.com) -- A newly developed vaccine aimed at blocking infection by the virus associated with half of all cervical cancers appears to be highly effective. See full story

Zapping prostate tumors with microwaves
SEATTLE – Nov. 27, 2001 (cancerfacts.com) -- Can microwaving prostate tumors kill them without harming nearby tissue? Researchers think the approach can work and early results of clinical trial are promising. See full story

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